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It is estimated that 95% of transcripts from multiexon genes undergo alternative splicing, some instances of which occur in a tissue-specific manner and/or under … Alternative splicing is a method cells use to create many proteins from the same strand of DNA. Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, JapanDepartment of Surgery, Tohoku University Graduate School of Medicine, SendaiPlease check your email for instructions on resetting your password. If you continue browsing the site, you agree to the use of cookies on this website. Scribd is the world's largest social reading and publishing site. Alternative splicing of mRNA precursors is a versatile mechanism of gene expression regulation that accounts for a considerable proportion of proteomic complexity in higher eukaryotes. Georgetown University Networks of coordinated alternative splicing (AS) events play critical roles in development and disease. In addition, we discuss the utilization of this information, so that future studies can continue to contribute to this field of research.The authors declare no competing interests.Enter your email address below.Enter your email address below and we will send you your username Alternative precursor messenger RNA (pre‐mRNA) splicing plays an important role in the generation of functional diversity of the genome. After transcription, introns need to be removed from the pre-mRNA by a step called splicing. Exons can be extended or skipped, or introns can be retained. Through this process, a single gene increases its coding capacity by expressing several related proteins with diverse and even antagonistic functions. The Alternative Splicing and Transcript Diversity database (ASTD) gives information about a huge collection of alternative transcripts combining transcription initiation, polyadenylation and splicing variant data and has now been intergrated into Ensembl genome browser .
Get the plugin now. alternative splicing of mrna. Forgot your username?Alternative precursor messenger RNA (pre‐mRNA) splicing.
Bucknell University 2. If you do not receive an email within 10 minutes, your email address may not be registered, and you may need to create a new Wiley Online Library account.If the address matches an existing account you will receive an email with instructions to retrieve your usernameCan't sign in? Alternative splicing, or alternative RNA splicing, or differential splicing, is a regulated process during
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