177LuPSMA-R2 is being developed to treat prostate cancer and 68GaPSMA-R2 is under development as its complementary diagnostic candidate.AAA currently has a total of 31 sites in 12 countries, including: 19 production facilities in 8 countries (in Europe and the U.S.) that manufacture targeted radioligand therapies and precision imaging radioligands, and 6 sites with R&D activity.
AAA has a broad pipeline of products in development, including several theragnostic pairings for oncology indications.
The idea is to develop complementary drug pairings targeting the same marker or receptor expressed on the tumor that may be used to both image and treat disease.Different kinds of radioisotopes are used for precision imaging and targeted therapy, depending on the type of energy they release. Some radioisotopes release gamma rays, such as fluorine 18 (F-18) or gallium 68 (Ga-68), which can be useful for imaging of disease to help determine extend and location of the disease. Novartis builds cancer pipeline with a new platform/drug buyout, bagging Advanced Accelerator Applications for $3.9B.
Advanced Accelerator Applications (AAA) is a radiopharmaceutical company that develops, produces and commercializes molecular nuclear medicine, or MNM, diagnostic and therapeutic products. Pipeline Our goal is to reimagine nuclear medicine. Our pipeline of investigational drugs includes several different radioisotopes.
Our goal is to reimagine nuclear medicine. AAA’s approach involves the combination of therapeutics and imaging diagnostics, which we call our oncology theragnostic platform. AAA is a global leader in the development of predictive, preventive and personalized tools that may transform healthcare for patients and physicians.
PSMA-R2 is a ligand of Prostate-Specific Membrane Antigen (PSMA), expressed on the majority of prostate tumor cells. Other radioisotopes, such as lutetium 177 (Lu-177) or actinium 225 (Ac-225) release beta particles or alpha particles, which can damage targeted cells with a therapeutic effect. We are an innovative medicines company developing a pipeline of targeted radioligand therapies and precision imaging radioligands for oncology.
CTT1057 is a phosphoramidate-based peptide, which specifically binds to Prostate-Specific Membrane Antigen (PSMA), expressed on the majority of prostate tumor cells.AAA has a broad pipeline of products in development, including several theragnostic pairings for oncology indications.177LuPSMA-R2 and 68GaPSMA-R2 are in development to treat, image, monitor and stage prostate cancer. John Carroll Editor & Founder. CTT1057 is an 18F-labeled investigational diagnostic candidate in development for PET imaging of prostate cancer. We are committed to transforming patients’ lives by leading innovation in nuclear medicine.
We are an innovative medicines company developing a pipeline of targeted radioligand therapies and precision imaging radioligands for oncology.AAA’s approach involves the combination of therapeutics and imaging diagnostics, which we call our oncology theragnostic platform. Advanced Accelerator Applications, S.A. (AAA), a Novartis company, is developing targeted radioligand therapies and precision imaging radioligands for oncology indications.
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